Sintilimab Biosimilar – Research Grade [ICH5001]

ichorbio’s Sintilmab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. This sintilimab biosimilar is for Research Use Only (RUO) and not for therapeutic use. Click here to view ichorbio’s complete list of anti-PD-1 antibodies and biosimilars.

ichorbio’s sintilimab biosimilar is available in the following sizes:
1mg, 5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our sintilimab biosimilar – please contact us for pricing.

PD-1

IgG4 kappa

Programmed cell death protein 1, Pdcd1, CD279

CHO cells

Human

Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sintilimab.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Sintilimab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.

1.0 – 5.0 mg/ml

Sterile, preservative-free, clear to milky white colorless to slightly yellow solution, containing L-histidine , polysorbate 80 and sucrose. pH set to 5.5. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Sintilimab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.

Bulk Human IgG4 Isotype Control (IB4) [ICH2257]