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Murinized anti-Mouse PD-1 (RMP1-14) Recombinant Antibody
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Murinized anti-Mouse PD-1 (RMP1-14) Recombinant Antibody
| Concentration | 1.0 - 5.0 mg/ml |
|---|---|
| Isotype | Mouse IgG2a |
| Host | Mouse |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | Western Blot, Blocking, Flow Cytometry, Functional Assays |
| Storage | Mouse anti-mouse PD-1 antibody (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Purification Method | This monoclonal antibody was purified using Protein A |
| Specificity | Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse PD-1 |
| Species Reactivity | Mouse |
| Target | PD-1 |
| Shipping Conditions | Blue ice |
| background | CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are memb |
| Other names | Programmed cell death protein 1, Pdcd1, CD279 |
| clone | RMP1-14 |
| UniProt | Q02242 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | Subset of double negative thymocytes, activated T and B cells |
| Immunogen | Mouse PD-1 transfected BHK cells |
| Aggregation | Aggregation level ≤ 5% |
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