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Lodapolimab Biosimilar - Research Grade
$710.00 - $6,900.00
Lodapolimab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
PDCD1ï؟½
Concentration
5mg/ml
Isotype
IgG1 - lambda
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q15116
Shipping Conditions
Blue ice
Background
Programmed cell death protein 1 (PD-1, encoded by PDCD1) is a central inhibitory checkpoint on activated T cells and a cornerstone target of immuno-oncology research. This human IgG1, lambda antibody is an unconjugated, non-therapeutic analog of lodapolimab that binds PD-1 for functional assays. It is purified to a low-endotoxin standard compatible with in vivo experiments and manufactured in scalable milligram-to-gram quantities to serve heavy-usage and high-throughput laboratories. Intended for research use only (RUO), it is suited to checkpoint-blockade studies, T-cell activation and exhaustion readouts, in vitro co-culture screening, and preclinical tumor immunology models, functioning as both control and active reagent.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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