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Gantenerumab Biosimilar - Research Grade
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Gantenerumab Biosimilar - Research Grade
| Species Reactivity | Human |
|---|---|
| Target | Beta Amyloid |
| Concentration | 5mg/ml |
| Isotype | Human IgG1 |
| Host | CHO cells |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
| Applications | Functional Assays |
| Storage | This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human Beta Amyloid. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Gantenerumab. |
| Shipping Conditions | Blue ice |
| background | RUO gantenerumab is a monoclonal antibody for the treatment of Alzheimerï؟½s disease being developed by Hoffmann-La Roche pharmaceuticals. Gantenerumab binds to and clears aggregated beta amyloid fibers. A phase III clinical trial of gantenerumab was stop |
| UniProt | P05067 |
| Buffer | ICH3002 |
| Sequence | https://www.imgt.org/mAb-DB/ |
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