Gantenerumab Biosimilar - Research Grade

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ICH5009
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$306.00

Gantenerumab Biosimilar - Research Grade

Product Details:

ichorbio's gantenerumab biosimilar is for Research Use Only (RUO)

Size:

ichorbio's RUO gantenerumab biosimilar is available in the following sizes: 1mg, 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar - please contact us for pricing.

Target:

Amyloid Beta

Isotype:

IgG1 kappa

Other Names:

Amyloid beta precursor protein, APP, ABPP

Host:

CHO cells

Species Reactivity:

Human

Specificity:

Detects human amyloid beta.

Purification Method:

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 1.0 EU/mg as determined by the LAL method

Storage:

Gantenerumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use: ichorbio's gantenerumab biosimilar is for research use only (RUO). Isotype Control:

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]

More Information
Concentration 9.11mg/ml
Isotype IgG1 kappa
Host CHO cells
Use Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications Functional Assays
Storage This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Endotoxin ≤ 1.0 EU/mg as determined by the LAL method
Purity >95% by SDS-PAGE
Formulation Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity Detects human Beta Amyloid. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Gantenerumab.
Species Reactivity Human
Target Beta Amyloid
Shipping Conditions Blue ice
background RUO gantenerumab is a monoclonal antibody for the treatment of Alzheimerï؟½s disease being developed by Hoffmann-La Roche pharmaceuticals. Gantenerumab binds to and clears aggregated beta amyloid fibers. A phase III clinical trial of gantenerumab was stop
UniProt P05067
Buffer ICH3002
Sequence https://www.imgt.org/mAb-DB/
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