Acrixolimab Biosimilar - Research Grade

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SKU
ICH5224
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$710.00 - $19,500.00
Delivery Time : 4 weeks

Acrixolimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
PD-1
Concentration
5mg/ml
Isotype
Human IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH2751
Uniprot
Q15116
Shipping Conditions
Blue ice
Background
As a key inhibitory checkpoint, PD-1 limits T-cell responses in tumours and chronic infection, a central node in immuno-oncology research. This recombinant anti-human PD-1 monoclonal is an unconjugated, non-therapeutic analog of acrixolimab, supplied for research use only (RUO). It is manufactured to in vivo standards, carries low endotoxin, and is produced in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Use it in functional assays, checkpoint-blockade and T-cell-reactivation studies, reproducible controls, and in vivo tumour models, relying on consistent lot-to-lot performance for large research campaigns.
Specificity
Detects human PD-1
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
4 weeks
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