Camrelizumab Biosimilar - Research Grade

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SKU
ICH5003
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$315.00 - $19,890.00

Camrelizumab Biosimilar - Research Grade

Endotoxin
<1 EU/mg Determined by LAL gel clotting assay
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
PD-1
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG4
Host
Humanized
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Camrelizumab.
Shipping Conditions
Blue ice
Background
The PD-1 checkpoint pathway limits T-cell activity and is a major focus of cancer-immunotherapy research. This research-grade reagent is an unconjugated, non-therapeutic analog of camrelizumab that recognises human PD-1 and supports functional assays. Manufactured to in vivo standards with low endotoxin, it is sold strictly for research use only and supplied in scalable milligram to gram quantities to meet high-throughput demand. Investigators apply it to checkpoint-blockade experiments, T-cell functional readouts, in vitro screening, in vivo immuno-oncology models, and comparative characterisation of biologics, supported by consistent batch-to-batch quality for demanding workflows.
Other Names
Programmed cell death protein 1, Pdcd1, CD279
Uniprot
Q15116
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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