Sintilimab Biosimilar - Research Grade

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SKU

ICH5001

$306.00

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Concentration	1.0 - 5.0 mg/ml
Isotype	Human IgG4
Host	Humanized
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications	Functional Assays
Storage	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles.
Endotoxin	<1EU/mg Determined by LAL gel clotting assay
Purity	>95% by SDS-PAGE and HPLC
Formulation	Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity	Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sintilimab.
Species Reactivity	Human
Target	PD-1
Shipping Conditions	Blue ice
background	Pembrolizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.
Other names	Programmed cell death protein 1, Pdcd1, CD279
UniProt	Q15116
Buffer	ICH3002
Sequence	https://www.imgt.org/mAb-DB/