Dostarlimab Biosimilar - Research Grade

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SKU
ICH5311
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$315.00 - $19,890.00

Dostarlimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
PD-1
Concentration
5mg/ml
Isotype
Human IgG4 (S228P)-kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q15116
Shipping Conditions
Blue ice
Background
PD-1 is an inhibitory checkpoint receptor that limits T-cell responses and remains a cornerstone target in cancer immunotherapy research. Offered as an unconjugated, non-therapeutic analog of dostarlimab, this research-grade anti-human PD-1 recombinant monoclonal antibody is intended for research use only (RUO). It is manufactured to in vivo quality standards, formulated for low endotoxin, and supplied in scalable milligram (mg) to gram (g) quantities for heavy-usage and high-throughput laboratories. Applications include checkpoint blockade assays, in vitro functional screening, and in vivo immuno-oncology models, where it provides a consistent control and reproducible active reagent.
Other Names
TSR-042,ANB-011,(programmed cell death 1, PD1, PD-1, CD279
Specificity
Detects human PD-1
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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