Bulk Nivolumab Biosimilar – Research Grade
ichorbio’s Nivolumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. Click here to view ichorbio’s complete list of anti-PD-1 antibodies and biosimilars.
ichorbio’s research grade nivolumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our nivolumab biosimilar – please contact us for pricing.
PD-1
n/a
IgG4 (S228P) kappa
Programmed cell death protein 1, Pdcd1, CD279
Humanized
Human
Detects human PD-1. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Nivolumab. This nivolumab biosimilar is for research use only (RUO).
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Nivolumab biosimilar is a human monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. Nivolumab is an IgG4 kappa immunoglobulin that has a calculated molecular mass of 146 kDa. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line.
1.0 – 5.0 mg/ml
Sterile, preservative-free, pyrogen-free, clear to milky white, colorless to pale yellow liquid, containing mannitol, gadopentetate, polysorbate 80, sodium chloride and sodium citrate dihydrate, pH value 6.0. BSA and Azide free.
>95% by SDS-PAGE and HPLC
≤ 0.75 EU/mg as determined by the LAL method
This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.
Functional Assays
Each investigator should determine their own optimal working dilution for specific applications.
ichorbio’s nivolumab biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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