Infliximab Biosimilar - Research Grade

Bulk Infliximab Biosimilar - Research Grade

ichorbio's infliximab Biosimilar - Research Grade is manufactured in a cGMP compliant facility.

ichorbio's research grade infliximab biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our infliximab biosimilar - please contact us for pricing.

TNF-alpha

n/a

IgG1 kappa

Humanized

Human

Detects human TNF-alpha.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Infliximab biosimilar is a chimeric IgG1κ monoclonal antibody (composed of human constant and murine variable regions) specific for human tumor necrosis factor-alpha (TNFα). It has a molecular weight of approximately 149.1 kilodaltons. Infliximab biosimilar is produced by a recombinant cell line cultured by suspension culture and is purified by a series of steps that includes measures to inactivate and remove viruses.

1.0 - 5.0 mg/ml

Sterile, clear, colorless, preservative-free solution with a pH of about 7.2, containing dihydrate Disodium hydrogen phosphate, sodium dihydrogen phosphate monohydrate, polysorbate 80, and sucrose.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Infliximab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]