Matuzumab Biosimilar - Research Grade

Bulk Matuzumab Biosimilar - Research Grade

Product Specific Citations:

Tikum et al. Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates. Pharmaceutics (2022).

Product Benefits:

ichorbio's matuzumab Biosimilar - Research Grade is manufactured in a cGMP compliant facility.

Size:

ichorbio's research grade matuzumab biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our matuzumab biosimilar - please contact us for pricing.

Target:

EGFR

Clone:

n/a

Isotype:

IgG1 kappa

Other Names:

Host:

Humanized

Species Reactivity:

Human

Specificity:

Detects human EGFR.

Purification Method:

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

Matuzumab biosimilar is a humanized IgG1 monoclonal antibody against human EGFR. As it only has approximately 10% murine origin it has limited immunogenicity, and being IgG1 it is capable of inducing antibody dependent cell cytotoxicity (ADCC).Matuzumab biosimilar is produced in mammalian (Chinese hamster ovary) cell culture.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, clear, colorless, preservative-free solution with a pH of about 7.2, containing dihydrate Disodium hydrogen phosphate, sodium dihydrogen phosphate monohydrate, polysorbate 80, and sucrose.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 0.75 EU/mg as determined by the LAL method

Storage:

Matuzumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use: ichorbio's matuzumab biosimilar is for research use only. Isotype Control:

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]