Anti-Mouse IL-1R (JAMA-147) In Vivo Antibody - Low Endotoxin

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SKU
ICH1117
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$400.00 - $2,945.00

Anti-Mouse IL-1R (JAMA-147) In Vivo Antibody - Low Endotoxin

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Mouse
Target
IL1R1
Concentration
1.0 - 5.0 mg/ml
Isotype
Armenian Hamster IgG
Host
Armenian Hamster
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Applications
Immunoprecipitation, Western Blot, Blocking, Flow Cytometry
Storage
anti-IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½20°C in a manual defrost freezer. Avoid
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purification Method
This monoclonal antibody was purified using Protein A
Specificity
Anti-IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) recognizes Mouse IL-1 R1
Shipping Conditions
Blue ice
Background
The IL-1 receptor type 1 (IL1R1) transduces IL-1 alpha and IL-1 beta signals to activate downstream inflammatory pathways central to innate immunity. Clone JAMA-147 is an Armenian hamster IgG monoclonal antibody to mouse IL-1R, validated for immunoprecipitation, Western blot, blocking and flow cytometry. Anti-mouse IL-1R JAMA-147 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. This non-therapeutic, research-use-only (RUO) reagent offers reproducible performance for studies of IL-1 signalling and inflammation in the mouse.
Other Names
Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a
Clone
JAMA-147
Uniprot
P13504
Buffer
ICH3001-100ml ICH3002-100ml ICH3003-100ml
Immunogen
Extracellular domain of mouse IL-1 R type 1
Aggregation
Aggregation level ≤ 5%
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