Anti-Mouse CD40 (FGK4.5) In Vivo Antibody - Low Endotoxin

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SKU
ICH1073
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$390.00

Bulk anti-CD40 In Vivo Antibody - Low Endotoxin (FGK4.5)

More Information
Product Specific Citations

Pircher et al. MHC I tetramer staining tends to overestimate the number of functionally relevant self-reactive CD8 T cells in the preimmune repertoire. European Journal of Immunology.

M. Stepanechko et al. Single Treatment Boiling Histotripsy Focused Ultrasound Ablation Neither Negates nor Enhances the Activity of α-CD40 in a Pancreatic Cancer Model. IEEE Transactions on Biomedical Engineering,

Concentration 1.0 - 5.0 mg/ml
Isotype Rat IgG2a
Host Rat
Use Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes Each investigator should determine their own optimal working dilution for specific applications.
Applications Western Blot, Functional Assays, Flow Cytometry
Storage anti-CD40 In Vivo Antibody - Low Endotoxin (FGK4.5) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles.
Endotoxin <0.5 EU/mg as determined by the LAL method
Purity >95% by SDS-PAGE and HPLC
Formulation 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added
Purification Method This monoclonal antibody was purified using Protein G
Specificity Anti-CD40 In Vivo Antibody - Low Endotoxin (FGK4.5) recognizes an epitope on Mouse CD40
Species Reactivity Mouse
Target CD40
Shipping Conditions Blue ice
background CD40, also known as TNFSF5, is a type I transmembrane protein and member of the TNF receptor family. The binding of CD40L (CD40) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 is expressed on B cel
clone FGK4.5
UniProt P27512
Buffer ICH3001-100ml ICH3002-100ml ICH3003-100ml
Antigen Distribution B cells, basal epithelial cells, macrophages, follicular dendritic cells, and endothelial cells
Immunogen Recombinant Mouse CD40 Fusion Protein
Aggregation Aggregation level ≤ 5%
Related Antibody Anti-CD40 In Vivo Antibody - Ultra Low Endotoxin [FGK4.5] (ICH1073UL)

Product Benefits:

ichorbio's anti-CD40 In Vivo Antibody - Low Endotoxin (FGK4.5) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility.

If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.5EU/mg) at an even higher purity (98% versus 95%).

Isotype Control:

Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)

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