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Anti-Mouse CD172a (P84) In Vivo Antibody - Low Endotoxin
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Anti-Mouse CD172a (P84) In Vivo Antibody - Low Endotoxin
| Concentration | 1.0 - 5.0 mg/ml |
|---|---|
| Isotype | Rat IgG1 Kappa |
| Host | Rat |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Blocking: Reported applications in literature include: blocking SIRPalpha interaction with CD47 & in vivo blocking of dendritic cell migration. Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | Western Blot, Blocking, Flow Cytometry, IHC (Frozen), Immunoprecipitation |
| Storage | anti-CD172a In Vivo Antibody - Low Endotoxin (P84) is stable when stored at 2-8°C. Do not freeze. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Purification Method | This monoclonal antibody was purified using Protein G |
| Specificity | Anti-CD172a In Vivo Antibody - Low Endotoxin (P84) recognizes an epitope on Mouse CD172a |
| Species Reactivity | Mouse |
| Target | CD172a |
| Shipping Conditions | Blue ice |
| background | Signal regulatory protein alpha (SIRPalpha), also known as CD172a, is a regulatory membrane type I glycoprotein from the SIRP family expressed mainly by myeloid cells and also by stem cells or neurons. |
| Other names | Sirpa, Sirp-alpha-1, SHP substrate 1, SHPS-1, Shps1, Bit, p84, MyD-1 antigen, Myd1, Ptpns1 |
| clone | P84 |
| UniProt | P97797 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | Monocytes, macrophages, myeloid cells, neuronal tissue |
| Immunogen | Mouse brain membrane protein |
| Aggregation | Aggregation level ≤ 5% |
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