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Human IgG4 Isotype Control S228P/F234A/L235A (Lambda)
$315.00 - $5,200.00
Human IgG4 Isotype Control S228P/F234A/L235A (Lambda)
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG4 (S228P/F234A/L235A)-Lambda1
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
This human IgG4 (S228P/F234A/L235A) isotype control with a lambda1 light chain delivers an effector-silenced, subclass-matched negative reference for studies using IgG4-lambda antibodies. The S228P change stabilises the hinge while the FALA substitutions abrogate Fcγ engagement, and the control's absence of specificity lets it define background and gating limits in functional and cytometric assays. Provided low in endotoxin and suitable for in vivo administration, it is produced at scalable milligram to gram quantities to meet the needs of bulk and high-throughput research. The antibody is non-therapeutic and supplied strictly for research use only.
Specificity
Human IgG4 (Lambda) with a S228P/F234A/L235A mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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