Nimotuzumab Biosimilar – Research Grade [ICH4008]

ichorbio’s Nimotuzumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility.

ichorbio’s research grade nimotuzumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our nimotuzumab biosimilar – please contact us for pricing.

EGFR

n/a

IgG1

Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1

Humanized

Human

Detects human EGFR. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Nimotuzumab. This nimotuzumab biosimilar is for research use only (RUO).

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Nimotuzumab biosimilar has a humanized human-mouse h-R3 heavy chain and a humanized human-mouse h-R3κ-chain. nimotuzumab binds to the epidermal growth factor receptor (EGFR), a signalling protein that normally controls cell division.

1.0 – 5.0 mg/ml

Sterile, clear, colorless solution without preservatives, containing sodium dihydrogen phosphate, phosphoric acid disodium hydrogen, sodium chloride and polysorbate 80. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.