Depatuxizumab Biosimilar - Research Grade

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SKU
ICH5294
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$315.00 - $19,890.00

Depatuxizumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
EGFR
Concentration
5mg/ml
Isotype
Human IgG1 (E356D/M358L)
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P00533;P00533;Q01279;Q01279;P00533
Shipping Conditions
Blue ice
Background
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that drives proliferation and survival signalling and is a heavily studied oncogenic target. This anti-human EGFR recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of depatuxizumab, intended strictly for research use only. Manufactured to demanding in vivo standards with a low-endotoxin formulation, it is supplied in scalable milligram (mg) to gram (g) quantities to serve bulk and high-throughput laboratories. It functions as a consistent control and active reagent in receptor-signalling assays, in vitro functional screening, ADCC studies, and in vivo tumour models.
Other Names
ABT-806;epidermal growth factor receptor, receptor tyrosine-protein kinase erbB-1, ERBB1, HER1, HER-1, ERBB
Specificity
Detects human EGFR
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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