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Sutimlimab Biosimilar - Research Grade
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Sutimlimab Biosimilar - Research Grade
| Concentration | 5mg/ml |
|---|---|
| Isotype | Human IgG4 |
| Host | CHO |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
| Applications | Functional Assays |
| Storage | This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human C1s. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sutimlimab. |
| Species Reactivity | Human |
| Target | C1s |
| Shipping Conditions | Blue ice |
| background | RUO sutimlimab biosimilar is a humanized monoclonal antibody that is designed to selectively target and inhibit C1s in the classical complement pathway, which is part of the innate immune system. By blocking C1s, sutimlimab inhibits the activation of the |
| Other names | EDSPD2, complement C1s |
| UniProt | P09871 |
| Buffer | ICH3002 |
| Sequence | https://www.imgt.org/mAb-DB/ |
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