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Etanercept Biosimilar - Research Grade
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Bulk Etanercept Biosimilar - Research Grade
Product Benefits:ichorbio's Etanercept Biosimilar - Research Grade is manufactured in a cGMP compliant facility. ichorbio: the best antibodies for in vivo research.
Size:ichorbio's research grade etanercept biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our etanercept biosimilar - please contact us for pricing.
Target:TNF
Clone:n/a
Isotype:n/a
Other Names:Benapali®; Enbrel®
Host:Humanized
Species Reactivity:Human
Specificity:Inhibits TNF. This product is for research use only.
Background:Etanercept biosimilar is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept biosimilar is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons.
Concentration:>5.0 mg/ml
Formulation:Sterile, preservative-free, clear, and colorless solution containing 10mM Tris +40g/L mannitol，pH7.5
Purity:>95% by SDS-PAGE and HPLC
Endotoxin:≤ 0.75 EU/mg as determined by the LAL method
Storage:Etanercept Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:Functional Assays
Application Notes:Each investigator should determine their own optimal working dilution for specific applications.
Use: ichorbio's Etanercept Biosimilar is for research use only (RUO).Bulk Etanercept Biosimilar - Research Grade
| Product Specific Citations | |
|---|---|
| Concentration | 6.52mg/ml |
| Isotype | n/a |
| Host | Humanized |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human TNF. This non-therapeutic fusion-protein uses the same sequence as the therapeutic Etanercept. |
| Species Reactivity | Human |
| Target | TNF alpha |
| Shipping Conditions | Blue ice |
| background | Etanercept biosimilar is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains |
| Other names | Tumor necrosis factor |
| UniProt | P01375 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Sequence | https://www.imgt.org/mAb-DB/ |
Product Benefits:
ichorbio's Etanercept Biosimilar - Research Grade is manufactured in a cGMP compliant facility. ichorbio: the best antibodies for in vivo research.
Size:ichorbio's research grade etanercept biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our etanercept biosimilar - please contact us for pricing.
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