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Certolizumab Biosimilar - Research Grade
$315.00 - $19,890.00
Certolizumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
TNFA
Concentration
5mg/ml
Isotype
Human Fab'-G1-kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P01375
Shipping Conditions
Blue ice
Background
Tumour necrosis factor alpha (TNF-alpha) is a key pro-inflammatory cytokine driving chronic inflammation in numerous autoimmune disease models. This recombinant anti-human TNF-alpha Fab' fragment is an unconjugated, non-therapeutic analog of certolizumab, intended strictly for research use only (RUO). Built to demanding in vivo standards and low in endotoxin, it is manufactured in scalable milligram (mg) to gram (g) quantities for high-throughput and heavy-usage laboratories. It serves as a dependable neutralizing control and active reagent in cytokine assays, in vitro functional screening, and in vivo inflammatory disease models, with consistent lot-to-lot performance.
Other Names
CDP870,PHA-738144,tumor necrosis factor (TNF) superfamily member 2, TNFSF2, TNF-alpha, TNFA
Specificity
Detects human TNFA
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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