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PM8002 Biosimilar - Research Grade
$365.00 - $9,364.00
PM8002 Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
VEGF + PD-L1
Concentration
5mg/ml
Isotype
Human IgG1(L234A/L235A/E356D/M358L)-kappa-VHH
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P15692;Q9NZQ7
Shipping Conditions
Blue ice
Background
Co-targeting VEGF-driven angiogenesis and PD-L1-mediated immune evasion is a leading combination strategy in cancer research, aimed at simultaneously normalizing tumour vasculature and relieving checkpoint suppression. This research-grade PM8002-type bispecific antibody is an unconjugated, non-therapeutic reagent engineered to bind both VEGF and PD-L1 for preclinical investigation of these intertwined pathways. Validated for functional assays and supplied for research use only (RUO), it is produced to in vivo grade standards as an ultra-pure, low-endotoxin preparation. With scalable milligram (mg) to gram (g) availability, it supports in vitro screening, in vivo tumour-immunology models and dual-mechanism characterization in high-throughput laboratories.
Purification Method
This monoclonal antibody was purified using IEC
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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