Gefurulimab Biosimilar - Research Grade

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SKU
ICH6023
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$515.00 - $8,600.00

Gefurulimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
C5 + ALB
Concentration
5mg/ml
Isotype
VH-VH
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P01031;Q8TES7
Shipping Conditions
Blue ice
Background
Complement component C5 sits at the heart of terminal complement activation, and blocking it is a long-studied approach in complement-mediated disease research; pairing C5 binding with albumin (ALB) engagement is one strategy explored to extend molecular persistence. This research-grade bispecific molecule is an unconjugated, non-therapeutic analog of gefurulimab built around C5 and albumin binding, intended strictly for research use only (RUO). Validated for functional assays and manufactured to in vivo grade standards as an ultra-pure, low-endotoxin formulation, it is supplied in scalable milligram (mg) to gram (g) quantities to support preclinical complement-pathway studies, neutralization assays and in vivo disease modelling in heavy-usage laboratories.
Purification Method
This monoclonal antibody was purified using IEC
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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