Linvoseltamab Biosimilar - Research Grade

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SKU
ICH6025
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$365.00 - $9,364.00

Linvoseltamab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CD3E + BCMA
Concentration
5mg/ml
Isotype
Human IgG4 (S228P)-kappa
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P07766;Q02223
Shipping Conditions
Blue ice
Background
T-cell-redirecting bispecific antibodies that link CD3 to a tumour antigen are a major focus of immuno-oncology, and BCMA is a validated plasma-cell and multiple-myeloma target. This research-grade bispecific antibody is an unconjugated, non-therapeutic analog of linvoseltamab, engineered to co-engage CD3E and BCMA for preclinical study of T-cell-mediated cytotoxicity. It is validated for functional assays and intended strictly for research use only (RUO). Manufactured to in vivo grade standards as an ultra-pure, low-endotoxin formulation and offered in scalable milligram (mg) to gram (g) quantities, it serves heavy-usage and high-throughput laboratories conducting cytotoxicity assays, in vitro screening and in vivo tumour models.
Purification Method
This monoclonal antibody was purified using IEC
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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