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Lebrikizumab Biosimilar - Research Grade
$315.00 - $19,890.00
Lebrikizumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
IL-13
Concentration
5mg/ml
Isotype
Human IgG4 S228P Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human IL-13. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Lebrikizumab.
Shipping Conditions
Blue ice
Background
Interleukin-13 (IL-13) is a Th2 cytokine driving allergic inflammation and tissue remodelling, and it is a central target in atopic-disease research. This research-grade antibody is an unconjugated, non-therapeutic analog of lebrikizumab that binds human IL-13 and is validated for functional assays. It is intended for research use only, purified to a low-endotoxin standard suitable for in vivo studies, and produced in scalable milligram to gram quantities for high-throughput laboratories. Applications include cytokine-neutralisation assays, Th2-signalling studies, in vitro screening, in vivo allergic-inflammation models, and biologics characterisation.
Uniprot
P35225
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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