Anti-Human/Monkey MDR-1 (UIC2) In Vivo Antibody - Low Endotoxin

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SKU
ICH1273
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$150.00 - $2,945.00

Anti-Human/Monkey MDR-1 (UIC2) In Vivo Antibody - Low Endotoxin

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human, Monkey
Target
MDR-1
Concentration
>1.0 mg/ml
Isotype
Mouse IgG2a
Host
Mouse
Aggregation
Aggregation level ≤ 5%
Buffer
ICH3002
Uniprot
P08183
Shipping Conditions
Blue ice
Background
MDR-1 (P-glycoprotein) is an efflux transporter that pumps diverse compounds out of cells and is a key determinant of multidrug resistance studied in pharmacology and oncology. Clone UIC2 is a mouse IgG2a monoclonal antibody recognizing human and monkey MDR-1, validated for flow cytometry, immunoprecipitation, immunofluorescence, and in vivo applications. Anti-MDR-1 clone UIC2 is supplied in a low-endotoxin format suitable for in vivo use and manufactured in scalable milligram to gram quantities for bulk and high-throughput laboratories. Researchers rely on UIC2 for reproducible transporter studies, with this reagent provided for research use only.
Other Names
P-gp, ABCB1, CD243, P-glycoprotein
Clone
UIC2
Specificity
MDR-1
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
Flow Cytometry, Immunoprecipitation, Immunofluorescence, in vivo
Application Notes
This antibody is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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