Izeltabart Biosimilar - Research Grade

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SKU
ICH5614
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Izeltabart Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
ADAM9ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q13443
Shipping Conditions
Blue ice
Background
ADAM9, a membrane metalloproteinase, contributes to extracellular-matrix remodeling and tumor progression, attracting attention as an oncology antigen. Built around the human protein, this reagent is an unconjugated, non-therapeutic analog of izeltabart, a human IgG1, kappa monoclonal supplied for research use only (RUO). Low endotoxin levels render it appropriate for in vivo studies, and manufacturing across milligram to gram scales ensures reliable supply for bulk and high-throughput pipelines. The antibody supports target-binding and internalization assays, in vitro screening, and preclinical tumor models, and as a non-therapeutic analog it can assist antibody-drug-conjugate (ADC) research without contributing any payload or linker chemistry.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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