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Izastobart Biosimilar - Research Grade
$710.00 - $6,900.00
Izastobart Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
C5AR1ï؟½
Concentration
5mg/ml
Isotype
IgG1 - lambda2
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P21730
Shipping Conditions
Blue ice
Background
The complement C5a receptor (C5AR1) transmits potent chemotactic and pro-inflammatory signals that shape innate immune responses. This unconjugated, non-therapeutic analog of izastobart is a recombinant human IgG1, lambda monoclonal against the human receptor, made available for research use only (RUO). Held to a low-endotoxin specification for in vivo compatibility, it is produced in scalable milligram to gram batches tailored to high-throughput and bulk laboratories. Typical uses include receptor-antagonism and neutralization assays, chemotaxis studies, in vitro screening, and preclinical inflammation models, where the antibody acts as a stable functional control supporting complement biology and biologics-characterization research.
Other Names
C5A, C5AR, C5R1, CD88, complement component 5a receptor 1, C5a receptor, complement C5a receptor 1
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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