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Bulk Anti-Human CD2 (LO-CD2a) In Vivo Antibody
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Bulk Anti-Human CD2 (LO-CD2a) In Vivo Antibody
| Concentration | ≤ 2.0 mg/ml |
|---|---|
| Isotype | Rat IgG2b Kappa |
| Host | Rat |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | ELISA, Functional Assays, Flow Cytometry |
| Storage | This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | <1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using Protein G |
| Specificity | Anti-CD2 antibody (clone LO-CD2a) activity is directed against human CD2. |
| Species Reactivity | Human |
| Target | CD2 |
| Shipping Conditions | Blue ice |
| background | LO-CD2a strongly inhibits mixed lymphocyte culture (MLC) 3 and induces T cell apoptosis. Additionally, LO-CD2a does not induce proliferation of resting T cells, and inhibits T cell proliferation induced by OKT3 antibody, induces very low levels of cytokin |
| Other names | BTI-322, CD2, CD2 molecule, T11, SRBC, LFA-2, T-cell surface antigen CD2, LFA-3 receptor, rosette receptor, erythrocyte receptor, lymphocyte-function antigen-2, T-cell surface antigen T11/Leu-5, CD2 antigen (p50), sheep red blood cell receptor |
| clone | LO-CD2a |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | CD2 is expressed on all mature human T cells, most thymocytes, NK cells and a small proportion of bone marrow cells. |
| Immunogen | LO-CD2a was developed as an immunosuppressive agent for use in organ allotransplantation. LO-CD2a was produced by immunizing a LOU/C rat with purified human T lymphocytes and fusing the splenocytes with the non-secreting rat fusion cell line IR983F, resul |
| Aggregation | Aggregation level ≤ 5% |
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