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Bulk Anti-Human CD18 (IB4) Antibody
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Bulk Anti-Human CD18 (IB4) Antibody
| Concentration | ≤ 2.0 mg/ml |
|---|---|
| Isotype | Mouse IgG2a Kappa |
| Host | Mouse |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | Functional Assays, Flow Cytometry, IF Microscopy |
| Storage | This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | <1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using Protein A |
| Specificity | Anti-CD18 antibody (clone 1B4) activity is directed against human CD18 and can also stain rabbit bone marrow leukocytes. |
| Species Reactivity | Human |
| Target | CD18 |
| Shipping Conditions | Blue ice |
| background | Murine (m) 1B4 was humanized (h) by the CDR-grafting method to create an anti-CD18 antibody with similar avidity, specificity, and efficacy as the murine antibody. In rhesus monkeys, h1B4 is less immunogenic than m1B4 and elicits only anti-idiotypic antib |
| Other names | Integrin beta-2, integrin beta chain, beta 2, ITGB2 |
| clone | 1B4 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | Depending on its heterodimeric configuration, CD18 is expressed in leukocytes, monocytes, macrophages, some lymphocytes, polymorphonuclear lymphocytes (PMNs), natural killer cells, neutrophils, granulocytes, certain lymphocytic tumor cell lines, macrophag |
| Immunogen | Human peripheral blood lymphocytes |
| Aggregation | Aggregation level ≤ 5% |
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