Anti-Mouse/rat MHC Class II (14-4-4S) In Vivo Antibody - Low Endotoxin

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SKU
ICH1247
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$561.00 - $4,080.00

Anti-Mouse/rat MHC Class II (14-4-4S) In Vivo Antibody - Low Endotoxin

Endotoxin
< 1.0 EU/mg as determined by the LAL method
Purity
≥95% monomer by analytical SEC_>95% by SDS Page
Species Reactivity
Mouse, Rat
Target
MHC Class II (I-Ek/RT1-D)
Concentration
>5mg/ml
Isotype
Mouse IgG2a Kappa
Host
Mouse
Shipping Conditions
Blue ice
Background
MHC class II molecules present extracellular-derived peptides to CD4 T cells, and the I-Ek/RT1-D antigens are key haplotype markers in mouse and rat immunology. Clone 14-4-4S is a mouse IgG2a kappa monoclonal antibody recognising these MHC class II molecules in mouse and rat, validated for functional assays, flow cytometry, IHC, and immunoprecipitation. Anti-MHC class II 14-4-4S is supplied in a low-endotoxin format suitable for in vivo use and manufactured in scalable milligram to gram quantities for bulk and high-throughput laboratories. As a research-use-only, non-therapeutic reagent, it provides reproducible performance for antigen-presentation and transplantation research.
Other Names
I-Ek/RT1-D
Clone
14-4-4S
Purification Method
Protein A
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Storage
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Applications
FA, FC, IHC, IP
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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