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Rovelizumab Biosimilar - Research Grade
$710.00 - $19,500.00
Rovelizumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
ITGAL, ITGB2
Concentration
5mg/ml
Isotype
Human IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH2992
Uniprot
P20701;P05107
Shipping Conditions
Blue ice
Background
The integrins ITGAL and ITGB2 together form LFA-1, a leukocyte adhesion molecule essential for immune-cell trafficking and immune-synapse formation. This anti-human ITGAL/ITGB2 recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of rovelizumab, intended strictly for research use only. Produced to rigorous in vivo standards with low endotoxin, it is manufactured in scalable milligram (mg) to gram (g) quantities to meet the needs of heavy-usage and high-throughput laboratories. It functions as a consistent control and active reagent in adhesion and migration assays, in vitro functional screening, and in vivo models of inflammation and immune cell trafficking.
Specificity
Detects human ITGAL, ITGB2
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
4 weeks
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