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Human IgG1 Isotype Control E356D/M358L/L234A/L235A/F405L
$315.00 - $5,200.00
Human IgG1 Isotype Control E356D/M358L/L234A/L235A/F405L
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (E356D/M358L/L234A/L235A/F405L)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
Combining allotype and effector-modifying Fc substitutions (E356D/M358L/L234A/L235A/F405L), this human IgG1-kappa isotype control provides a matched, non-binding reference for human IgG1 experiments, including bispecific and Fc-engineering work where the F405L mutation supports controlled Fab-arm exchange. It is used for background, gating, and negative-control purposes in functional and in vivo studies. Supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities, it serves bulk and high-throughput laboratories. The antibody is non-therapeutic and intended strictly for research use only, offering reproducible, lot-consistent control performance.
Specificity
Human IgG1 with a E356D/M358L/L234A/L235A/F405L mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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