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Gotistobart Biosimilar - Research Grade
$710.00 - $6,900.00
Gotistobart Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CTLA4ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P09793;P16410
Shipping Conditions
Blue ice
Background
CTLA-4, encoded by CTLA4, is an inhibitory immune checkpoint that restrains T-cell activation and a cornerstone target of immuno-oncology research. We supply a research-grade anti-CTLA-4 recombinant monoclonal antibody, an unconjugated, non-therapeutic analog of gotistobart, intended for research use only (RUO). Built to rigorous in vivo standards, this ultra-pure, low-endotoxin formulation ships in scalable milligram (mg) to gram (g) quantities to serve heavy-usage and high-throughput laboratories. It supports checkpoint-blockade studies, receptor-ligand inhibition and ADCC assays, in vitro screening, control reagent use, and in vivo tumor immunology models.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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