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Anti-Mouse CD32/CD16 (2.4G2) In Vivo Antibody - Low Endotoxin
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Anti-Mouse CD32/CD16 (2.4G2) In Vivo Antibody - Low Endotoxin
| Concentration | 0.5 mg/ml |
|---|---|
| Isotype | Rat IgG2b |
| Host | Rat |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | Western Blot, Blocking, Flow cytometry, IHC (Frozen), Immunoprecipitation, CODEX |
| Storage | anti-CD32/CD16 In Vivo Antibody - Low Endotoxin (2.4G2) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Purification Method | This monoclonal antibody was purified using Protein G |
| Specificity | Anti-CD32/CD16 In Vivo Antibody - Low Endotoxin (2.4G2) recognizes the Fc_II and Fc_III receptors |
| Species Reactivity | Mouse |
| Target | CD32/CD16 |
| Shipping Conditions | Blue ice |
| background | CD16 is a low-affinity IgG Fc receptor III and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive |
| Other names | Low affinity immunoglobulin gamma Fc region receptor II, Fcgr2, Fc-gamma-RIIB, FcRII, IgG Fc receptor II beta, Ly-17, Low affinity immunoglobulin gamma Fc region receptor III, Fcgr3, FcRIII, Fc-gamma RIII |
| clone | 2.4G2 |
| UniProt | P08508 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | The Fc gamma II/III receptors are present on mouse natural killer cells, monocytes, macrophages, granulocytes, B-cells and most fetal thymocytes. |
| Aggregation | Aggregation level ≤ 5% |
| Antibodies against the same target | Anti-CD16 In Vivo Antibody - Low Endotoxin [3G8] (ICH1010) |
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