Human IgG1 Isotype Control FES

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SKU
ICH2254FES
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$315.00 - $5,200.00

Human IgG1 Isotype Control FES

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (K214R/L234F/L235E/P331S)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
Designated FES (K214R/L234F/L235E/P331S), this human IgG1-kappa isotype control carries Fc mutations that reduce effector engagement, supplying an effector-attenuated, non-binding reference for human IgG1 experiments. It is used to define background signal, set flow-cytometry gating, and serve as a negative control in functional and in vivo studies. The antibody is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities to serve bulk and high-throughput laboratories. As a non-therapeutic, research-use-only reagent, it delivers reproducible, lot-consistent control performance across antibody-engineering and immunology workflows.
Specificity
Human IgG1 with a FES mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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