Tislelizumab Biosimilar - Research Grade

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SKU

ICH5004

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$306.00

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Tislelizumab Biosimilar - Research Grade
Product Benefits:

ichorbio's Tislelizumab Biosimilar - Research Grade is manufactured in a cGMP compliant facility. Click here to view ichorbio’s complete list of anti-PD-1 antibodies and biosimilars.

Size:

ichorbio's Tislelizumab biosimilar is available in the following sizes: 1mg, 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our Tislelizumab biosimilar - please contact us for pricing.

Target:

PD-1

Isotype:

IgG4 kappa

Other Names:

Programmed cell death protein 1, Pdcd1, CD279

Host:

CHO cells

Species Reactivity:

Human

Specificity:

Detects human PD-1.

Purification Method:

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

Tislelizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, preservative-free, clear to milky white colorless to slightly yellow solution, containing L-histidine , polysorbate 80 and sucrose. pH set to 5.5. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 0.75 EU/mg as determined by the LAL method

Storage:

Tislelizumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control:

Bulk Human IgG4 Isotype Control (IB4) [ICH2257]

Use: ichorbio's Tislelizumab biosimilar is for research use only (RUO).

More Information
Concentration	9.48mg/ml
Isotype	IgG4 kappa
Host	CHO cells
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications	Functional Assays
Storage	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles.
Endotoxin	<1 EU/mg Determined by LAL gel clotting assay
Purity	>95% by SDS-PAGE and HPLC
Formulation	Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity	Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Tislelizumab.
Species Reactivity	Human
Target	PD-1
Shipping Conditions	Blue ice
background	Pembrolizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.
Other names	Programmed cell death protein 1, Pdcd1, CD279
UniProt	Q15116
Buffer	ICH3002
Sequence	https://www.imgt.org/mAb-DB/