Back to Top
Mapatumumab Biosimilar - Research Grade
Mapatumumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
TNFRSF10Aï؟½
Concentration
5mg/ml
Isotype
IgG1 - nd
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
O00220
Shipping Conditions
Blue ice
Background
TNFRSF10A (DR4) is a death receptor that transmits apoptotic signals upon TRAIL engagement, a pathway of enduring interest in cancer cell-death research. This research-grade anti-human TNFRSF10A recombinant monoclonal is an unconjugated, non-therapeutic analog of mapatumumab supplied for research use only (RUO). The formulation is low in endotoxin to permit in vivo experimentation and is manufactured in scalable milligram-to-gram quantities so heavy-usage and high-throughput laboratories stay well provisioned. It functions effectively as an agonistic or control reagent in apoptosis assays, in vitro tumor cell screening, receptor-clustering studies, and preclinical in vivo oncology models, as well as broader biologics characterization.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
Write Your Own Review















