Sotigalimab Biosimilar - Research Grade

Human

CD40

5mg/ml

Human IgG1 (S267E/E356D/M358L/KDel)-Kappa

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human CD40. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sotigalimab.

Blue ice

CD40 engagement on dendritic cells and B cells licenses robust T-cell priming, a mechanism heavily investigated in cancer-immunology research. This research-grade antibody is an unconjugated, non-therapeutic analog of sotigalimab targeting human CD40 and validated for functional assays. It is sold strictly for research use only, supplied in a low-endotoxin format suitable for in vivo work, and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. Investigators apply it to CD40-agonism assays, immune-activation studies, in vitro screening, in vivo immuno-oncology models, and comparator work in biologics development.

APX005M

P27512

ICH3002

https://www.imgt.org/mAb-DB/