Bevacizumab Biosimilar - Research Grade

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SKU

ICH4003

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$306.00

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Bulk Bevacizumab Biosimilar - Research Grade

Product Benefits:

ichorbio's Bevacizumab Biosimilar - Research Grade is manufactured in a cGMP compliant facility. ichorbio's bevacizumab biosimilar is strictly for research use only (RUO).

Size:

ichorbio's research grade bevacizumab biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our bevacizumab biosimilar - please contact us for pricing.

Target:

VEGF

Clone:

n/a

Isotype:

IgG1

Other Names:

Vascular Endothelial Growth Factor

Host:

Humanized

Species Reactivity:

Human

Specificity:

Detects human VEGF.

Purification Method:

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

Bevacizumab biosimilar is vascular endothelial growth factor directed antibody. Bevacizumab biosimilar is a recombinant humanized monoclonal IgG1 antibody that contains human framework regions and murine complementarity-determining regions. Bevacizumab biosimilar has an approximate molecular weight of 149 kDa. Bevacizumab is produced in a mammalian cell (Chinese Hamster Ovary) expression system in a nutrient medium.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, clear or slightly milky white, colorless to light brown liquid, containing trehalose, monobasic sodium phosphate monohydrate, sodium dihydrogen phosphate and Tween 20. pH 6.2. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 0.75 EU/mg as determined by the LAL method

Storage:

Bevacizumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use: ichorbio's bevacizumab biosimilar is for research use only (RUO). Isotype Control:

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]

More Information
Concentration	11.2mg/ml
Isotype	IgG1
Host	Humanized
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Purity	>95% by SDS-PAGE and HPLC
Formulation	Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity	Detects human VEGF. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Bevacizumab.
Species Reactivity	Human
Target	VEGF
Shipping Conditions	Blue ice
background	Bevacizumab biosimilar is vascular endothelial growth factor directed antibody. Bevacizumab biosimilar is a recombinant humanized monoclonal IgG1 antibody that contains human framework regions and murine complementarity-determining regions. Bevacizumab bi
Other names	Vascular endothelial growth factor
UniProt	P15692
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml
Sequence	https://www.imgt.org/mAb-DB/