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Anti-Human HLA-DQ (1a3) Antibody: Fc Biotinylated
$200.00 - $1,700.00
Anti-Human HLA-DQ (1a3) Antibody: Fc Biotinylated
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
HLA-DQ
Concentration
1.0 mg/ml
Isotype
Mouse IgG2a
Host
Mouse
Aggregation
Aggregation level ≤ 5%
Antigen Distribution
The HLA-DQ antigen is present on approximately 10% of peripheral blood lymphocytes. This antibody reacts with virtually all B-cell lines and some tissue macrophages and dendritic cells.
Buffer
ICH3002
Uniprot
P01906
Shipping Conditions
Blue ice
Background
HLA-DQ is an MHC class II molecule that presents peptides to CD4 T cells and is closely linked to autoimmune-disease susceptibility. Clone 1a3 is a mouse IgG2a monoclonal antibody against human HLA-DQ, validated for flow cytometry and ELISA, and this preparation is Fc-biotinylated to enable streptavidin-based detection systems. Anti-HLA-DQ clone 1a3 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. With dependable lot-to-lot performance, 1a3 supports reproducible HLA class II research, offered strictly for research use only.
Other Names
HLA-DQ Monomorphic
Clone
1a3
Specificity
Anti-HLA-DQ In Vivo Antibody - Low Endotoxin (1a3) recognizes a monomorphic epitope present on HLA-DQ molecules of the human class II major histocompatibility complex (MHC). anti-HLA-DQ does not react with HLA-DR or HLA-DP molecules.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
This Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Applications
Flow Cytometry, ELISA
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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