Natalizumab Biosimilar - Research Grade

Human

CD49d

5mg/ml

Human IgG4 Kappa

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human CD49d

Blue ice

CD49d is the alpha4 integrin subunit involved in leukocyte adhesion and trafficking across the blood-brain barrier and inflamed tissue, a well-studied target in neuroinflammation. This research-grade antibody is an unconjugated, non-therapeutic analog of natalizumab recognising human CD49d and validated for functional assays. It is intended for research use only, formulated to a low-endotoxin specification suitable for in vivo work, and produced in scalable milligram to gram quantities for high-throughput laboratories. It supports adhesion-blockade studies, leukocyte-migration assays, in vitro screening, and in vivo models exploring integrin-dependent immune cell trafficking.

ITGA4, CD49D, IA4, integrin subunit alpha 4

P13612

ICH3001-100ml ICH3002-100ml ICH3003-100ml

https://www.imgt.org/mAb-DB/