Natalizumab Biosimilar – Research Grade [ICH4037]

ichorbio’s Natalizumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility.

ichorbio’s research grade natalizumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our natalizumab biosimilar – research grade. Please contact us for pricing.

α4β1 integrin

n/a

Human IgG4

alpha-4 integrin

Humanized

Human

Detects human α4β1 integrin. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody TYSABRI. This product is for research use only.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Natalizumab biosimilar – research grade is a humanized monoclonal antibody that blocks α4β1 integrin. It is an IgG1 kappa immunoglobulin with an approximate molecular weight of 149 kDa.

1.0 – 5.0 mg/ml

Sterile, preservative-free, buffer includes sodium chloride; sodium phosphate, monobasic, monohydrate; sodium phosphate, dibasic, heptahydrate; polysorbate 80, pH 6.1. BSA and Azide free.

>98% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

Natalizumab is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.

Bulk Human IgG4 Isotype Control (IB4) [ICH2257]