Bulk Natalizumab Biosimilar – Research Grade
ichorbio’s Natalizumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility.
ichorbio’s research grade natalizumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our natalizumab biosimilar – research grade. Please contact us for pricing.
α4β1 integrin
n/a
Human IgG4
alpha-4 integrin
Humanized
Human
Detects human α4β1 integrin. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody TYSABRI. This product is for research use only.
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Natalizumab biosimilar – research grade is a humanized monoclonal antibody that blocks α4β1 integrin. It is an IgG1 kappa immunoglobulin with an approximate molecular weight of 149 kDa.
1.0 – 5.0 mg/ml
Sterile, preservative-free, buffer includes sodium chloride; sodium phosphate, monobasic, monohydrate; sodium phosphate, dibasic, heptahydrate; polysorbate 80, pH 6.1. BSA and Azide free.
>98% by SDS-PAGE and HPLC
≤ 1.0 EU/mg as determined by the LAL method
Natalizumab is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Functional Assays
Each investigator should determine their own optimal working dilution for specific applications.
ichorbio’s natalizumab biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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