Secukinumab Biosimilar - Research Grade

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SKU

ICH4033

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$306.00

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Bulk Secukinumab Biosimilar - Research Grade

Product Benefits:

ichorbio's Secukinumab Biosimilar - Research Grade is manufactured in a cGMP compliant facility.

Size:

ichorbio's research grade secukinumab biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg,100mg ichorbio regularly manufactures bulk multi-gram amounts of our secukinumab biosimilar - please contact us for pricing.

Target:

IL-17A

Clone:

n/a

Isotype:

IgG1 kappa

Other Names:

Interleukin-17A, IL17A, CTLA-8, CTLA8

Host:

Humanized

Species Reactivity:

Human

Specificity:

Detects human IL17A.

Purification Method:

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

Secukinumab is a recombinant human monoclonal IgG1/κ antibody that binds specifically to IL-17A. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Secukinumab has a molecular mass of approximately 151 kDa; both heavy chains of secukinumab contain oligosaccharide chains.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, preservative-free, clear to milky white, colorless to slightly yellow solution, with a pH of 5.8, containing L-histidine/histidine monohydrate hydrochloride, polysorbate 80, and sucrose. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 0.75 EU/mg as determined by the LAL method

Storage:

Secukinumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use: ichorbio's secukinumab biosimilar is for research use only (RUO). Isotype Control:

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]

More Information
Concentration	8.75mg/ml
Isotype	IgG1 kappa
Host	Humanized
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Purity	>95% by SDS-PAGE and HPLC
Formulation	Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity	Detects human IL17A. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Secukinumab.
Species Reactivity	Human
Target	IL17A
Shipping Conditions	Blue ice
background	Secukinumab is a recombinant human monoclonal IgG1/_ antibody that binds specifically to IL-17A. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Secukinumab has a molecular mass of approximately 151 kDa; both heavy chains of secuki
Other names	Interleukin-17A, IL17A, CTLA-8, CTLA8
UniProt	Q16552
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml
Sequence	https://www.imgt.org/mAb-DB/