Ragifilimab Biosimilar - Research Grade

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SKU
ICH5800
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Ragifilimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
TNFRSF18ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q9Y5U5
Shipping Conditions
Blue ice
Background
TNFRSF18 (GITR) is a co-stimulatory TNF-receptor-superfamily molecule that shapes T-cell and regulatory-T-cell function. This research-grade human IgG1 kappa antibody is an unconjugated, non-therapeutic analog of ragifilimab, generated in CHO cells against human TNFRSF18. For research use only, it is formulated to low endotoxin for in vivo compatibility and offered in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. It supports receptor-agonism and functional T-cell assays, Treg modulation studies, ADCC investigations, and preclinical tumor-immunity models. Its reproducible quality supports demanding workflows that consume reagent at scale.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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