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Marmoset CD32b Protein (In Vivo Grade, Ultra-Low Endotoxin)
Marmoset CD32b Protein (In Vivo Grade, Ultra-Low Endotoxin)
Endotoxin
<1.0 EU per mg as determined by the LAL method.
Purity
>95% monomer purity as determined by SDS-PAGE and SEC-HPLC.
Species Reactivity
Marmoset (Callithrix jacchus)
Target
Marmoset CD32b Protein
Host
Human embryonic kidney (HEK) 293 cells
Uniprot
A0A8I3W6Y8
Shipping Conditions
Ambient
Background
As the inhibitory Fc gamma receptor, CD32b (FcγRIIb) sets activation thresholds on immune cells, and its marmoset form supports translational studies in a key non-human-primate model. This recombinant marmoset CD32b ectodomain is expressed in HEK 293 cells and validated for SPR, BLI and ELISA, providing a defined tool for measuring inhibitory-receptor engagement and comparing Fc binding across species. Supplied for research use only in an in vivo grade, ultra-low-endotoxin format, it is produced in scalable milligram (mg) to gram (g) quantities, allowing bulk and high-throughput laboratories to characterize primate inhibitory Fc receptor function with reproducible material.
Other Names
CD32, CD32B, FCGR2, FCGR2B, FCGRII, FCGRIIB, FCR2, FCR2B, FCRII, FCRIIB, IGFR2, IGFR2B, IGFRII, IGFRIIB, Fc gamma R2, Fc gamma R2b, Fc gamma RII, Fc gamma RIIb, Fcg R2, Fcg R2b, Fcg RII, Fcg RIIb
Specificity
The sequence of the extracellular domain of marmoset CD32b (Gln 34-Met 215) was fused with a C-terminal tag consisting of the AVI tag, TEV protease recognition sequence and a 10-His tag.
Formulation
Lyophilized from sterile PBS, pH 7.4. No preservatives or cryoprotectants have been added. To obtain a final concentration of 1 mg/ml reconstitute 0.25 mg vials with 0.25 ml water and 1.0 mg vials with 1.0 ml water.
Storage
Lyophilized proteins are stable at ambient temperature for at least 2 weeks. If the protein is not to be used immediately then the protein should be stored in lyophilized form at -20 °C for up 12 months. Once the protein has been reconstituted we recommen
Applications
SPR, BLI, ELISA
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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