Manelimab Biosimilar - Research Grade

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SKU
ICH5667
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$315.00 - $3,902.00

Manelimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
PD-L1
Concentration
5mg/ml
Isotype
IgG1 - lambda2
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q9NZQ7
Shipping Conditions
Blue ice
Background
PD-L1 is a pivotal immune checkpoint ligand that dampens T-cell responses and underlies much of contemporary tumor-immunology research. Provided as an unconjugated, non-therapeutic analog of manelimab, this human anti-PD-L1 recombinant monoclonal (IgG1, lambda2) is for research use only (RUO). It is purified to low endotoxin so it can be applied in vivo, and it is generated in scalable milligram through gram batches to satisfy bulk and high-throughput laboratory programs. Investigators may employ it as a benchmark control and functional reagent across checkpoint-blockade assays, in vitro T-cell screening, ADCC evaluation, and preclinical in vivo immuno-oncology models.
Other Names
CD274ï؟½
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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