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Atibuclimab Biosimilar - Research Grade
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Atibuclimab Biosimilar - Research Grade
| Concentration | 5mg/ml |
|---|---|
| Isotype | Human IgG4 |
| Host | CHO cells |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
| Applications | Functional Assays |
| Storage | This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human CD14. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Atibuclimab. |
| Species Reactivity | Human |
| Target | CD14 |
| Shipping Conditions | Blue ice |
| background | RUO atibuclimab is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. It acts as a pattern recognition receptor for bacterial cell wall components in gram-positive and negative bacteria. CD14 antibody action stimulates |
| Other names | cluster of differentiation 14 |
| UniProt | P08571 |
| Buffer | ICH3002 |
| Sequence | https://www.imgt.org/mAb-DB/ |
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