Latozinemab Biosimilar - Research Grade

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SKU
ICH5629
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Latozinemab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
SORT1ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q99523
Shipping Conditions
Blue ice
Background
Sortilin (SORT1) is a sorting receptor implicated in progranulin trafficking and increasingly studied in neurodegeneration. Offered as a human IgG1, kappa antibody, this reagent is an unconjugated, non-therapeutic analog of latozinemab that binds SORT1 for functional and neuroscience research. The formulation carries a low endotoxin burden appropriate for in vivo work and is manufactured in scalable milligram-to-gram amounts to serve heavy-usage and high-throughput groups. Distributed for research use only (RUO), it functions as a control and active probe in receptor-modulation studies, progranulin pathway assays, in vitro binding panels, and preclinical models of neurodegenerative disease.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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