Mouse CD16a Protein (In Vivo Grade, Ultra-Low Endotoxin)

Mouse

Mouse CD16a Protein

Human embryonic kidney (HEK) 293 cells

P08508

Ambient

Mouse CD16a (FcγRIII) is an activating Fc gamma receptor central to NK-cell and macrophage effector responses, widely used as a reference receptor in preclinical antibody-effector research. This recombinant mouse CD16a ectodomain is expressed in HEK 293 cells and validated for SPR, BLI and ELISA, providing a defined tool for Fc binding kinetics and ADCC-related characterization in murine systems. The protein is supplied for research use only in an in vivo grade, ultra-low-endotoxin format and produced at scalable milligram (mg) to gram (g) scale, giving bulk and high-throughput laboratories a reproducible murine activating Fc receptor reagent.

CD16, CD16A, FCGR3, FCGR3A, FCGRIII, FCGRIIIA, FCR3, FCR3A, FCRIII, FCRIIIA, IGFR3, IGFR3A, IGFRIII, IGFRIIIA, Fc gamma R3, Fc gamma R3a, Fc gamma RIII, Fc gamma RIIIa, Fcg R3, Fcg R3a, Fcg RIII, Fcg RIIIa

The sequence of the extracellular domain of mouse CD16a (Leu 32-Thr 215) was fused with a C-terminal tag consisting of the AVI tag, TEV protease recognition sequence and a 10-His tag.

Lyophilized from sterile PBS, pH 7.4. No preservatives or cryoprotectants have been added. To obtain a final concentration of 1 mg/ml reconstitute 0.25 mg vials with 0.25 ml water and 1.0 mg vials with 1.0 ml water.

Lyophilized proteins are stable at ambient temperature for at least 2 weeks. If the protein is not to be used immediately then the protein should be stored in lyophilized form at -20 °C for up 12 months. Once the protein has been reconstituted we recommen

SPR, BLI, ELISA

Products are for research use only. Not for use in diagnostic or therapeutic procedures.