Human IgG1 Kappa Isotype Control - MMAE(PEG8) DAR4

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SKU
ICH2254-M4
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$1,220.00 - $4,355.00

Human IgG1 Kappa Isotype Control - MMAE(PEG8) DAR4

Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
>95% Determined by SDS-PAGE
Species Reactivity
Human
Target
Hen Egg Lysozyme
Isotype
Human IgG1
Buffer
ICH3001
Shipping Conditions
Blue ice
Background
Distinguishing target-specific activity from payload-driven effects is essential in antibody-drug-conjugate research, and this control is built for that purpose. Targeting hen egg lysozyme, an antigen with no mammalian counterpart, this human IgG1 kappa isotype control provides no specific binding and acts as a matched negative control. It is conjugated with MMAE via a PEG8 linker at a drug-to-antibody ratio of 4 (DAR4), allowing researchers to benchmark linker-payload chemistry while setting background and gating in functional assays. Offered as a research-use-only reagent in a low-endotoxin format suitable for in vivo use, it is produced in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput studies.
Formulation
PBS, pH 7.4, Contains no stabilizers or preservatives. 0.2 μM filtered
Storage
The product should be stored in the original stock concentration at 4°C. Avoid freeze / thaw cycles.
Use
Research Use Only. Not for Therapeutic or Diagnostic Use
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