Human IgG1 Kappa Isotype Control - Deruxtecan DAR8

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SKU
ICH2254-D8
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$1,220.00 - $4,355.00

Human IgG1 Kappa Isotype Control - Deruxtecan DAR8

Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
>95% Determined by SDS-PAGE
Species Reactivity
Human
Target
Hen Egg Lysozyme
Isotype
Human IgG1
Buffer
ICH3001
Shipping Conditions
Blue ice
Background
Interpreting antibody-drug-conjugate experiments requires a payload-matched control that carries no target specificity. Raised against hen egg lysozyme, an antigen not present in mammalian tissues, this human IgG1 kappa isotype control delivers no on-target binding and functions as a dependable negative reference. It is conjugated with deruxtecan at a drug-to-antibody ratio of 8 (DAR8), enabling researchers to isolate the contributions of payload and high-DAR loading from antigen-driven effects when establishing background and gating. The reagent is research use only, supplied in a low-endotoxin format suitable for in vivo use and manufactured in scalable milligram (mg) to gram (g) quantities for heavy-usage and high-throughput ADC studies.
Formulation
PBS, pH 7.4, Contains no stabilizers or preservatives. 0.2 μM filtered
Storage
The product should be stored in the original stock concentration at 4°C. Avoid freeze / thaw cycles.
Use
Research Use Only. Not for Therapeutic or Diagnostic Use
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